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Revista de la Facultad de Medicina Humana

English Title

Severe acute hepatitis by coinfection by epstein-barr viruses and citomegalovirus - case report and review of literature

Keywords

Hepatitis viral, Citomegalovirus, Ebstein-barr

English Keywords

Viral hepatitis, Cytomegalovirus, Epstein-barr

Abstract

Se reporta el caso de una paciente de 6 años con antecedente de dermatitis atópica. Días antes de hospitalizarse presentó rinorrea y tos. Posteriormente presentó lesiones maculopapulares, alza térmica y coloración amarillenta de la piel. Luego de ser hospitalizada, además de los síntomas descritos, presentó 2 episodios de epistaxis espontánea, hematemesis y melena; mientras que en el examen físico se evidencio ictericia mucocutánea, fiebre, rash maculopapular generalizado, adenopatías, y hepatoesplenomegalia. En el estudio de imágenes se encontraron signos que indicaron indirectamente hepatitis aguda y derrame pleural. Por otro lado, entre los resultados serológicos se encontró que los marcadores de infección aguda por VEB y CMV, al igual que el marcador de infección crónica por VEB, fueron positivos.

English Abstract

We report the case of a 6-year-old patient with a history of atopic dermatitis. Some days before her hospitalization she presented rhinorrhea and cough. Subsequently she presented maculopapular lesions, increase of body temperature and yellowing of the skin. After being hospitalized, in addition to the symptoms described, she presented 2 episodes of spontaneous epistaxis, hematemesis and melena; while in the physical examination, mucocutaneous jaundice, fever, generalized maculopapular rash, lymphadenopathy, and hepatosplenomegaly were evident. In the images studies, signs that indirectly indicated acute hepatitis and pleural effusion, were found. On the other hand, among the serological results, it was found that the markers of acute infection by EBV and CMV, as well as the marker of chronic EBV infection, were positive.

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